tory 1% of cases can
  lead to severe complications such as adhesive ileus (SKN)
  (Ellis 1997), and reoperation to increase the risk of adhesions and their complications
  (Ugur M. et al., 1996; Lundorff P. et al., 1996, Ellis et al, 1999). Traditional
  adhesive disease treatments are ineffective, and the frequent relapses of the disease
  after the surgical treatment and high mortality (3,0-9,45%, in early
  SKN 17-20% (Dronov AF, et al., 1997)), forced to seek new approaches to solving
  this problem.

purpose of research - studying the possibility of applying the gel of methylcellulose (MC)
  for intraperitoneal administration to prevent postoperative SPBP.

Of the group of naturally occurring polymers, the highest value in medicine
  and pharmacy purchased cellulose ethers including methylcellulose (MC). Gel
  based on it, according to the literature, non-toxic, physiologically inert and has
  biological stability, large adsorption, emulsifying, wetting
  and adhesion. When applying the gel on peritoneal MC cover bodies
  he, having good surface properties, covers the abdominal organs
  and the inner surface of the abdominal wall, providing preventive protivospaechny
  effect (Douldson MP, Dtasy PB, 1997; Chary RB, Vani G, Raj YM, 1999;
  Vlachou M. at al., 2001).

In the first phase of research to obtain information about the absence of any
  was the influence of MC on the gel intact peritoneum (the method of puncture in the abdominal cavity
  injected with 2 ml of 3% methylcellulose gel). After this, two series of rats
  Wistar rats (30 animals each) in sterile conditions simulated SPBP, and
  The first series was a control group, while the second - a pilot. Animals of the second series deserozirovannye
  sections of peritoneum treated with 3% methylcellulose gel. On day 14 of the control
  series of spikes occurred in all animals, the severity of adhesions by
  semantic differential was 3,39 ±
  0.18 points. In the experimental series in only four animals occurred podpaivanie
  gland to the median postoperative scar, and the severity of adhesions
  semantic differential method was 0,02 ±
  0.001 points (P <0,0001).

Thus, the research results prove the effectiveness of
  the use of MC and its gel to prevent postoperative SPBP in the experiment,
  which opens up prospects for its clinical application.

Lipatov, VA, Bachurina EI Rationality of methylcellulose
  for intraperitoneal administration in the prevention of postoperative adhesions
  abdominal cavity. Proceedings of the 67 th Inter-University Scientific Conference for Students
  and young scientists. In 2 parts. Part 2 .- Kursk: CSMU, 2002, sir. 125 - 126.