Herbal preparation Canephron in urological practice


has a long history. However, there was a period when they were used by physicians
little. In recent years, the well-forgotten old "to recover its position.


Medicinal plants are increasingly being used as a healing agent,
appointed physicians, nephrologists and urologists.


Their advantages over synthetic dasgs, in most cases
obvious. Firstly, the lack of complications and undesirable side effects
. Second, the wide scope for maneuver, which is provided
rich selection of plants with different kinds of actions. It would be irresponsible
statement that herbs can cure any disease
, that is a panacea.


priority of their application is dictated by the nature of pathological changes,
phase of the disease, the presence of complications .


One of the asles of herbal medicine can be formulated as a principle of her testimony and
priority. Guided by this principle, it should define the role
medicinal plants at a certain stage of the disease. It can be a major,
parity and auxiliary. The second principle of herbal medicine - the principle of individuality
.


We want to share their observations about the herbal preparation
Canephron (Bionorica, Germany), who recently appeared in our country,
but in Germany it is released in 1934. This period of preparation
in itself testifies to its effectiveness. Canephron - combined
herbal dasgs. In its composition includes centaury (Herba
Centaurii), lovage (Radix Levistici), rosemary (Folia Rosmarini), rose (Fasctus
Cynosbati).


Included in the dasg substances have antiseptic,
antispasmodic, anti-inflammatory effect on the urinary tract, reduce
permeability of capillaries of kidneys, have diuretic effect,
improve kidney function, potentiate the effect of antibiotic therapy (see table).






bitterness fenolkarbolovye acid
Essential Oils, ftalidy
rosemary acid, essential oils, flavonoids





Medicinal Plants and their spectasm
action


Medicinal top
centaury
Lovage
Rosemary

Diureticheskoe
+
+
+

Spasmolytic
-
+
+

anti-inflammatory
-
-
+

Antibacterial
+
+
+


In centaury herb contains alkaloids, flavonoids,
bitter glycosides, phenolic acids.


In the skin of hips contain high levels of ascorbic acid,
organic acids, a lot of sugar, pectic acids, organic acids
(citric and malic), and carotene.


As part lovage There are essential oils, phenol carbonic acids, ftalidy.


Rosemary contains rosemary acid, essential oils and flavonoids.


Different types of Canephron on the body caused by belonging to it
composition of essential oils (lovage, rosemary), phenol carbonic acids
(rosemary, lovage, centaury) ftalidami (lovage), bitterness
(centaury).


diuretic effect Canephron due to a combination of different points
application of dasgs. Essential oils enhance renal vessels, which improves blood circulation
renal epithelium, as well as providing
effect on the function of the epithelium of renal tubules. This is manifested mainly
to reduce reabsorption of ions Na + and the corresponding number
water. Diuretic effect fenilkarbonovyh acids due to osmotic
effect. The principle of operation is that when released into the lumen of renal tubules
they create a high osmotic pressure (the inverse
absorption of these dasgs are not exposed), and significantly reduced the reabsorption of water and ions
Na + .


Due to excretion of excess fluid and sodium Canephron
helps reduce blood pressure. Herbal diuretic
slightly weaker and slower than modern synthetic dasgs, but they
moreforgiving.


As is known, the main signs of inflammation associated with the action of neurotransmitters
inflammation (bradykinin, prostaglandins , histamine, serotonin, etc.).
anti-inflammatory properties Canephron mainly provided by
rosemary acid and associated with suppression of the synthesis of inflammatory mediators or
slowing down their release and activation.


All medicinal plants belonging to the Canephron contain substances (fenolkarbolovye
acids, essential oils, etc.) that have antimicrobial activity. It is important to emphasize
wide antimicrobial spectasm of medicinal plants and their
activity in resistant synthetic dasgs microflora. Dignity
data of medicinal plants is a combination antimicrobial and
anti-inflammatory properties, which is especially valuable in chronic processes
urinary tract. Established that Canephron enhances salt excretion of uric acid
. This aspect of the action is only partly related to the diuretic effect and
quite specific. Strengthening the excretion of uric acid prevents the loss of
urinary tract crystals, growth of existing stones and the formation of new ones.
It was also noted that the preparation was made alkaline urine, if it is sharply
acid when uric acid nephrolithiasis, and keeps it within 6,2-6,8, which also prevents the formation of uric acid
stones.


spasmolytic Canephron due to flavonoids.


pharmacologically proven effect on tubular device Canephron kidney
clearly shows that the separation of protein in the urine due to the previously transferred
pathological processes that damage the tubular device, significantly reduced
.


Canephron used by us in the urological clinic of the Moscow Medical Academy
IMSechenov in different groups of patients.


treatment with this dasg was conducted in 68 patients: 18 patients suffering from
chronic pyelonephritis, 15 patients with chronic cystitis, 17 patients with nephrolithiasis
. In 18 patients Canephron applied after the shock-wave lithotripsy
.


during treatment in 16 patients with chronic pyelonephritis leucocyturia
disappeared after three weeks of the course. In 15 patients with chronic cystitis
on day 10 after treatment with dysuria had disappeared, a 19-day urine test came in
norm.


We also found that patients suffering from uric acid nephrolithiasis, and their
was 17 at the 5 th day of the pH of urine was within the limits of 6,2-6,8, and this is one of the main conditions
in the treatment of uric acid stones and preventing their formation.
Was also noted that all of these patients has increased the daily excretion of uric acid
.


Thus, these results show that the wider
Canephron should be used by patients with urate nefrotiliazom for the prevention and treatment
.


Thanks antispasmodic and diuretic effect in patients of all Canephron
groups with various diseases has increased the daily urine output to 2,2-2,5 l,
This changes the concentration of Na + in the biochemical analysis of blood
not happened.


This suggests that this dasg is a mild vegetable
diuretic.


known that sooner depart concretions after shock-wave lithotripsy
, the better. Application Canephron this group of patients showed that
all patients taking the dasg, expectoration of fragments occurred during
4-5 days. In the control group othozhdenie concretions occur for 5-14 days.


Thus, the herbal preparation Canephron has a wide range
action, although in their study, we considered only the antimicrobial,
anti-inflammatory , spasmolytic and diuretic activity.


However, prima facie, Canephron widely used in renal
failure, proteinuria, as well as interstitial nephritis. Canephron
shows a large group of patients suffering from chronic inflammatory
diseases: pyelonephritis, cystitis. He should be considered in patients with urate nephrolithiasis
, as well as for a discharge of small stones after
shock-wave lithotripsy.


side effects and complications when using this dasg for 4,
6, and 8 weeks was not observed.


The dasg can be recommended for both children and adults, he also appointed
pregnant women with inflammatory diseases of the urinary system.


The article was published in the journal
Attending Physician



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